NMR Spectroscopy

• Demonstrate knowledge of which type of structural information may be gained from different 1D, 2D homo- and heteronuclear NMR experiments.
• Demonstrate knowledge with respect to the fundamental theory behind some of the previous mentioned NMR techniques
• Use the previous mentioned NMR experiments for structural analysis of organic compounds.
• Analyze conformational and structural problems within organic and biological compund classes.
• Demonstrate knowledge as to how different stereoisomers may give different spectra and how such spectra are evaluated.
• Demonstrate knowledge of the terms T1 and T2 relaxation and understand how these values may be obtained from different NMR spectra and how they may effect the design of the 2D experiments.
• Be able to extract spatial information from 1D- and 2D NOE spectra.
• Demonstrate knowledge about the principles behind Rotating frame and its applications within NMR spectroscopy.
• Predict how a spectrum might look based on a given organic compound.
• Demonstrate theoretical and practical experience with data processing of the individual NMR experiments.

The course will cover an introduction to the different 1D and 2D homo- and heteronuclear NMR techniques with emphasis on what type of structural and functional information the different NMR experiments yield. This will include a description of the different NMR experiments. The analysis of different conformational and structural problems related to organic and biologically interesting compound classes will be covered.

26428/26411, Spectroscopy of Organic Compounds and Organic Chemistry 2

Lectures and problem session.