Single-Course English 5 ECTS

Molecular biology

Overall Course Objectives

To give students a basic knowledge of molecular biology in both pro- and eukaryotes, as well as a knowledge of methods and paradigms, so that the students can follow a professional discussion as well as read molecular biology litterature.

Learning Objectives

  • Explain the mechanisms behind DNA replication, transcription and translation, as well as homologous recombination.
  • Identify structural genes in a DNA sequence (open reading frame with start and stop codons).
  • Identify promoters, terminators and operator sequences in a bacterial DNA sequence (consensus and degenerate sequences).
  • Explain the mechanisms in the formation of eukaryotic mRNA molecules, from initiation of transcription over splicing to transport of the mature mRNA to the cytoplasm.
  • Explain the molecular mechanisms of prokaryotic regulation of transcriptional initiation and leader termination (repression, activation and attenuation) as well as translation initiation and protein modification.
  • Explain the molecular mechanisms of eukaryotic regulation of transcriptional initiation (enhancers and silencers), histone modification, and epigenetic gene regulation.
  • Describe genetic elements: plasmids, insertion elements and transposons.
  • Describe the lifecycles of temperate and virulent viruses, as well as explain the gene-regulatory mechanisms that form the basis of the virus development.
  • Discuss mutagenesis and evolution in nature and in biotechnology research.
  • Discuss molecular biology experimental results using the above skills.

Course Content

Macromolecular synthesis (DNA, RNA and protein synthesis) and regulation of gene expression in both pro- and eukaryotes. Viruses and bacteriophages. Genetic elements – plasmids, insertion elements and transposons. Mutation and evolution.

Recommended prerequisites

23932/27002/27008/27020/12701, or equivalent.

Teaching Method

Lectures and exercises

See course in the course database.





13 weeks




DTU Lyngby Campus

Course code 27026
Course type Bachelor
Semester start Week 35
Semester end Week 48
Days Mon 13-17

7.500,00 DKK