Practical Organic Chemistry

• Perform multistep synthesis of organic compounds under aqueous and non-aqueous conditions.
• Explain the theoretical chemistry related to the reactions performed.
• Rationalise the choice of work-up procedures and purification methods for reactions performed.
• Monitor the progress of reactions using TLC and use this analysis to optimise the conversion.
• Purify compounds by column chromatography, recrystallisation and distillation.
• Identify products and assess purity by qualitative (GC, TLC), spectroscopic (IR and NMR) and physical (melting point, boiling point, optical rotation) methods.
• Work safely and independently in the laboratory.
• Record experiments and observations correctly in a lab journal.
• Access information about and evaluate of risk factors for the chemicals used and procedures performed.
• Evaluate completed syntheses and propose modifications to optimise reactions.

More advanced organic syntheses compared to 26003 Chemical Synthesis and 26474 Organic and Inorganic Synthesis.
Multi-step syntheses including e.g. Grignard reactions, electrophilic aromatic substitution, oxidations, reactions with carbanions, reactions with carbonyl compounds, resolution, carbohydrate synthesis, diazo compounds.

• 36 – 49 (Wed 8-17)
• 36 – 49 (Mon 13-17)
• 36 – 49 (Tues 8-12)
• 6 – 20 (Wed 8-17)
• 6 – 20 (Mon 13-17)
• 6 – 20 (Tues 8-12)

26411, Organic Chemistry 2

1 day a week. Laboratory exercises.

Maximum: 24.

Please be aware that this course has a limited number of seats available. If there are too many applicants, a pool will be created for the remainder of the qualified applicants, and they will be selected at random. You will be informed 8 days before the start of the course, whether you have been allocated a spot.