Recovery and purification of biological products

• Arrange unit operations into an appropriate sequence for the recovery of a given type of biological product.
• Clarify the interplay between upstream and downstream processes.
• Argue the need for bio-intensification.
• Apply use of hybrid and integrated processes
• Apply the principles for the recovery of small-molecules
• Apply the principles for the recovery of monoclonal antibodies
• Apply the principles for the recovery of enzymes
• Apply the principles for the recovery of human growth hormone

General introduction to industrial downstream processing form bio-processes. Principles of process design and development of downstream processing strategies. Effect of fermentation on downstream processing (upstream versus downstream). Separation principles and their effectiveness.

Chemistry/Chemical engineering/Biotech. bachelor or equivalent

Lectures and exercises

The quiz, which is considered an assignment, will take place on the last day of the course (week 13) during the lecture and not on the official date of the exam (as it is not an exam). So attendance to the last lecture of the course is mandatory.